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. 2019 Sep 12;19:911. doi: 10.1186/s12885-019-6091-5

Fig. 4.

Fig. 4

Influence of L1 siRNA on apoptosis-related signaling pathways in glioma cells. Western blot analysis of expression levels of phosphorylated Akt1 (a, d, g) and phosphorylated Erk1/2 (b, e, h), and ratio of Bcl-2/Bax (c, f, i) of U-87 MG, U251 and SHG44 cells after treatment with L1 siRNA. Mean values ± SEM are from 4 independent experiments; one-way ANOVA with Tukey’s post-hoc test. *p < 0.05 and **p < 0.001 versus Control siRNA group