Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Sep 12;7:249. doi: 10.1186/s40425-019-0695-9

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 1 — No difference in bulk CD8+ T cells phenotype at baseline or following treatment between atezolizumab responders and non-responders. a Frequencies of CD8+ T cells positive for all assessed marker molecules at baseline. b Frequencies of major CD8+ T cell subsets (naïve: CD45RO-,CCR7+; central memory: CD45RO+,CCR7+; effector memory: CD45RO+,CCR7-; effector: CD45RO-,CCR7-; and activated cells: CD38+/CCR7-) at baseline and on atezolizumab treatment. Each dot represents a patient. c Representative t-SNE map visualizing CD8+ T cells from one responder and one non-responder at baseline and on atezolizumab treatment with related plots showing relative position of cells expressing CD45RO, CCR7 and CD38. d Frequencies of CD8+ T cells positive for all analyzed markers at baseline and on atezolizumab treatment. Data shown from responders (green, n = 6) and non-responders (blue, n = 3)