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. Author manuscript; available in PMC: 2020 Feb 20.
Published in final edited form as: Bioconjug Chem. 2018 Nov 15;30(2):443–453. doi: 10.1021/acs.bioconjchem.8b00723

Figure 3.

Figure 3.

Confocal microscopy of GNR–siRNA carriers with co-adsorbed HS-PEG-folate internalized by SKOV-3 cells. siRNA duplexes are DTC-anchored and labeled with a fluorescent dye (Dy547). (a,b) SKOV-3 cells after 24-h incubation with GNR–(Dy547)siRNA (85 pM) plus control (Ctrl–); (c) SYBR Green I counterstain of nuclear dsDNA and cytoplasmic RNA; (d) Overlay of a and c showing cytoplasmic localization of GNR–siRNA. Bar = 30 μm.