Table 1.

Body weight, hemodynamics, RSNA, and endocrine data obtained from db/db mice and their wild-type controls

Parameter	Control mice	db/db mice
Body weight (g)	31 ± 1	53 ± 1*
MAP (mmHg)	84 ± 1	96 ± 2*
HR (bpm)	308 ± 5	352 ± 28
RSNA (v × sec/min)	1.3 ± 0.03	1.8 ± 0.10*
Leptin (ng/ml)	7 ± 1	220 ± 48*
Insulin (ng/ml)	1.08 ± 0.15	19.6 ± 3.00*

Body weight, MAP, HR, and RSNA were obtained at baseline, whereas endocrine parameters (plasma leptin and insulin) were measured at the end of the protocol. HR, Heart rate; MAP, mean arterial pressure; RSNA, renal sympathetic nerve activity. Data are mean ± SEM of 49 control mice and 48 db/db mice. ^*p<0.0001 versus control mice.