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. 2003 Oct 1;23(26):8989–9003. doi: 10.1523/JNEUROSCI.23-26-08989.2003

Figure 4.

Figure 4.

Immunohistochemical localization of the inflammatory response markers CD45 (a-c) and GFAP (d-f) in the hippocampal formation and frontolateral cortex, respectively, of a nontransgenic control (a, d) and a 13-month-old transgenic mouse (b, c, e, f). Note the absence of CD45 and GFAP immunoreactivities, i.e., microglioses and astroglioses, respectively, in the control but their discrete localization in the transgenic brain. CA1, Ammon's horn layer 1; cc, corpus callosum; Ctx, neocortex; DGgr, dentate gyrus granular layer; s, subiculum. Scale bars: a, b, d, e, 200 μm; c, f, 50 μm.