Somatotopic patterns in Drg11-/- and wild-type mice. A-J, CO staining of the whisker-like patterns in the PrV (A,B), VPm (C,D), S1 cortex (E,F, tangential section), SpVi (G,H), and SpVc (I,J). Note the absence of CO-stained patterns in the mutant PrV (B), VPm (D), and S1 cortex (F) but the presence of the patterns in the SpVi (H) and SpVc (J) of Drg11-/- mice. In the VPl thalamus and S1 cortex of the mutant, forepaw digit patterns were present (C,F, arrows). M,O, NADPH expression exhibits whisker-like patterns in the PrV (M) and S1 cortex (O) of wild-type mice and their absence in Drg11-/- mice (N, P). K,L, CO staining of the hindpaw digit patterns in the gracile nucleus (GN) of wild-type (K) mice and in the mutant (L). I-II, laminae I and II of the SpVc; III-IV, laminae III and IV of the SpVc; wp, whiskerpad representation; fp, forepaw representation. Scale bars, 100 μm.