Effects of SL327 and U0126 on animal behavior in a large open field. a, Large open field locomotion time for the lithium (Li)/SL327 interaction experiment (F(3,28) = 3.7; p < 0.03). b, Large open field distance traveled for the Li/SL327 interaction experiment (F(3,28) = 6.15; p < 0.01; post hoc test, SL327 group different than all other groups). Large open field locomotion time (c) and large open field distance (d) traveled for the U0126/DMSO comparison (NS).