Figure 1.

Mutations in glr-1 do not impair short-term habituation at a 60 sec ISI. Mean response magnitude in pixels for wild-type (a) and n2461 (b) worms given 20 taps at a 60 sec ISI (ky176 does not respond to taps). Data are presented averaged into 10 bins of two responses each. Both groups show a similar gradual decrease in response magnitude with repeated stimulation. Mean response magnitude in pixels for wild-type (c), n2461 (d), and ky176 (e) worms given 20 trains of taps (1 train is equivalent to 6 taps within 600 msec) at a 60 sec ISI. Data are presented averaged into 10 bins of two responses each, as above. All groups show a similar gradual decrease in response magnitude with repeated stimulation. Paired comparisons between bin 1 (average response to the first two stimuli) and bin 10 (average response across the last two stimuli) were significant in all cases with adjustment for multiple comparisons (N2 taps, t₍₁₉₎ = 4.73, p < 0.01; n2461 taps, t₍₁₉₎ = 3.21, p < 0.05; N2 trains, t₍₁₇₎ = 3.82, p < 0.05; n2461 trains, t₍₁₈₎ = 5.11, p < 0.01; ky176 trains, t₍₁₅₎ = 4.33, p < 0.01).