Table 1.
Characterization of inspiratory bursts recorded from the pre-Bötzinger complex of rat medullary slice preparations isolated from perinatal rats
|
Age |
n |
Interval (sec) |
Duration (sec) |
Amplitude (mV) |
Coefficient of variation of burst interval |
Delay onset (sec) |
|---|---|---|---|---|---|---|
| E16.5 | 5 | 40 ± 15* | 1.3 ± 0.14* | 11 ± 6.1* | 0.38 | 0.72 ± 0.15* |
| E17.5 | 8 | 24 ± 8.7* | 1.0 ± 0.12* | 19 ± 5.7* | 0.36 | 0.45 ± 0.11* |
| E18.5 | 4 | 18 ± 7.0* | 0.9 ± 0.13* | 23 ± 6.9 | 0.39 | 0.34 ± 0.12* |
| E19.5 | 4 | 14 ± 5.1* | 0.82 ± 0.10 | 21 ± 7.9 | 0.36 | 0.21 ± 0.09* |
| E20.5 | 5 | 8.8 ± 3.1 | 0.74 ± 0.09 | 25 ± 6.4 | 0.35 | 0.12 ± 0.07 |
| P2
|
5
|
6.7 ± 2.3
|
0.72 ± 0.10
|
27 ± 7.2
|
0.34
|
0.10 ± 0.07
|
The mean interburst interval, duration, and amplitude of inspiratory bursts were calculated from suction electrode recordings of population inspiratory discharge within the region of the pre-BötC of medullary slice preparations from perinatal rats. The delay onset refers to the relative timing of the onset of inspiratory bursts recorded from the XII nucleus inspiratory discharge relative to that recorded within the pre-BötC. Results are means ± SD; n is the number of preparations examined.
p < 0.05 compared with P2, Student's t test.