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Impaired carotid body function in P2X2-deficient mice. The plot of average firing rate (in spikes per second) of the whole nerve activity during hypoxic challenges. Data from P2X2+/+ (n = 7), P2X3+/+ (n = 7), and P2X2/P2X3Dbl+/+ (n = 8) mice are combined. *p < 0.05 and **p < 0.01 indicate significant difference compared with the wild-type animals (Student's t test).
