Skip to main content
. 2003 Dec 10;23(36):11363–11372. doi: 10.1523/JNEUROSCI.23-36-11363.2003

Figure 4.

Figure 4.

Strong dendritic depolarization can initiate dendritic spikes that precede somatic APs. A, Somatic (left), dendritic (middle; 175 μm from the soma), and superimposed (right; note different time scale bar) recordings of APs generated by just-suprathreshold dendritic current injection (top) or a larger dendritic current injection capable of generating a dendritically initiated spike (bottom). B, Somatic (left) and dendritic (middle; 185 μm from the soma) responses to weak (top) or strong (bottom) distal dendritic synaptic stimulation (delivered in layer 2/3). The superimposed traces (right; different time scale bar) demonstrate that strong synaptic input can generate dendritic spikes that precede somatic action potentials.