Figure 1.

Electrophysiological responses of distinct neuronal subtypes of the striatum to the injection of depolarizing and hyperpolarizing current steps. Note that whereas medium spiny projection neurons (MS) exhibit tonic firing activity with little afterhyperpolarization during positive current pulses, LA and FS interneurons present distinct firing patterns and pronounced afterhyperpolarizations. The dotted line represents the resting membrane potential of the three neurons. See Results for further details.