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. 2003 Jul 16;23(15):6245–6254. doi: 10.1523/JNEUROSCI.23-15-06245.2003

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Copyright © 2003 Society for Neuroscience 0270-6474/03/236245-10.00/0

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Figure 5. — Stimulation of DA D2-like receptor inhibits GABAergic synaptic transmission in WT but not in D2R-/- mice. A, The graph shows the dose-dependent inhibition of GABAergic synaptic transmission by quinpirole in LA interneurons of WT but not D2R-/- mice. The traces from single experiments show the effect of 10 μm quinpirole on IPSCs recorded from LA neurons of WT and D2R-/- animals. B, The graph shows the dose-dependent inhibition of GABAergic synaptic transmission by quinpirole in FS interneurons from WT and D2R-/- mice. Similar to LA cells, FS interneurons from the D2R-/- group are not sensitive to quinpirole. The traces from single experiments show the effect of 10 μm quinpirole on IPSCs recorded from FS neurons of WT and D2R-/- animals.