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Effects of quinpirole on GABAergic sIPSCs recorded from LA interneurons of WT, D2R-/-, D2L-/-, and D2R-/-;D2L-/- mice. The graphs are single-cell plots from patch-clamp experiments. In a WT LA interneuron (A), 10 μm quinpirole reduces the frequency of sIPSCs (expressed as inter-event interval). The effect of quinpirole is absent in the D2R-/- LA neuron (B), although it is similar to WTs in the D2L-/- cell (C). In D2R-/-;D2L-/- LA interneurons (D), the effect of quinpirole is reduced.
