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MTII depolarized MC4-R/GFP neurons in a hypothalamic slice preparation. Whole-cell recordings were performed on MC4-R/GFP neurons held in current clamp. A sample recording from an MC4-R neuron treated with 100 nm MTII is shown. Mean effect: 2.47 ± 1.17 mV; n = 14; p = 0.028.
