Table 2.

Quantification of PrP^c labeling on the membrane in different neuronal populations in the CA1 area and dentate gyrus^a

Neurons	Endoplasmic reticulum	Golgi complex	Endosomes/lysosomes	Plasma membrane	Mitochondria
Pyramidal (n = 18)	0.44 ± 0.03	0.71 ± 0.03	1.4 ± 0.2	1.37 ± 0.11	0.037 ± 0.002
Hilar (n = 18)	0.23 ± 0.01	0.4 ± 0.01	0.59 ± 0.06	0.58 ± 0.04	0.03 ± 0.01
Granule (n = 21)	0.25 ± 0.01	0.36 ± 0.03	0.58 ± 0.07	0.64 ± 0.03	0.03 ± 0.01
CPrP cells (n = 20)	0.38 ± 0.02	0.64 ± 0.05	1.51 ± 0.12	1.53 ± 0.08	0.06 ± 0.008

^a Values are number of gold particles per 1 μm of membrane (gold per micrometer) in 77 cells from three different animals, given as mean ± SEM. Mitochondrial membranes were used to assess background labeling.