Figure 4.

Apparently normal biochemical differentiation of cortical inhibitory neurons. A, Coronal sections (40 μm) of primary visual cortex from 3-week-old mice processed for parvalbumin, calbindin, NPY, and calretinin immunoreactivity revealed no gross differences in expression pattern. B, Quantification of calbindin- and parvalbumin-positive neurons from primary visual cortex of 2-, 3-, and 5-week-old WT and KO mice revealed no differences between the genotypes (p > 0.05, n = 3 mice per genotype). C, The ratio of GABA⁺/NeuN⁺ neurons is not significantly different at 5 weeks of age (p > 0.05, n = 3 mice per genotype).