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. 2003 Aug 20;23(20):7659–7669. doi: 10.1523/JNEUROSCI.23-20-07659.2003

Figure 5.

Figure 5.

Distribution of synaptic (perisynaptic vs active-zone) plasma membrane-apposed group I mGluR immunogold labeling in dendrites and spines of striatal neurons. A, Relative distribution of gold particles in relation to asymmetric (putative glutamatergic) and symmetric (putative GABAergic) synapses. Numbers of gold particles (g) and elements (e) examined were as follows: mGluR1a spines, 97 (g) and 81 (e); mGluR5 spines, 85 (g) and 71(e); mGluR1a dendrites, 40 (g) and 32 (e); and mGluR5 dendrites, 101 (g) and 62 (e). B, An example of perisynaptic gold-particle labeling for mGluR1a (arrow) at an axospinous asymmetric synapse (arrowheads). C, An example of gold-particle labeling for mGluR5 (arrows) apposed to the active zone of an axodendritic symmetric synapse (arrowheads). Sp, Spines; den, dendrites; t, axon terminals. Scale bar: (in B) B, C, 0.25 μm.