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Time course of nociceptive withdrawal reflex (NWR) adaptation after complete sensory block. Tails were depilated and EMLA-treated in A (P14-P21) and B (P17-P24). Arrows indicate start and end of treatment (↑ and ↓, respectively). The error rate of heat-nociceptive withdrawal reflex before and up to 5 d after treatment is shown. *p < 0.05; **p < 0.01; ns, not significant. The χ2 test was used for statistics.
