Figure 1.
The effect of MDMA on locomotor activity. MDMA (12 mg/kg) administration led to a long-lasting inhibition of locomotor activity in both normal (drug naive) and MPTP-treated, l-DOPA-unprimed common marmosets compared with normal vehicle-treated common marmosets (a). Comparison of the mean motor activity over a period of 8 hr shows a significant MDMA-mediated inhibition of motor activity in both MPTP-treated (l-DOPA unprimed) and normal (drug naive) common marmosets. *p < 0.05 (n = 4-6).