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. 2003 Oct 8;23(27):9107–9115. doi: 10.1523/JNEUROSCI.23-27-09107.2003

Figure 2.

Figure 2.

Dose-dependent effect of MDMA on motor activity (a, b) and motor disability (c, d) in MPTP-treated, l-DOPA-primed common marmosets. MDMA dose dependently inhibited the motor activity over a period of 8 hr, but compared with control (MPTP treated, l-DOPA-primed) animals, only at 6 mg/kg was the effect of MDMA on motor activity statistically significant (*p < 0.05). MDMA only transiently improved motor disability (c). d, Mean motor disability in 60 min segments. MDMA (12 mg/kg) significantly (p < 0.05) improved motor disability during the first 60 min after its administration; thereafter motor disability was not different or it worsened compared with control.