Figure 11.

Structure of hair bundles in heterozygous and homozygous Ptprq-TM-KO mice. High-magnification scanning electron micrographs of the hair bundles of inner (a, b) and outer (c, d) hair cells in the organ of Corti (basal coil) of heterozygous (a, c) and homozygous (b, d) Ptprq-TM-KO mice at P15. Note the loss of stereocilia from the hair bundles of homozygous mutant hair cells, the giant, fused stereocilia on the homozygous mutant inner hair cells (b), and how the stereocilia are shorter on the homozygous mutant outer hair cells (d). Scale bars, 1 μm.