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. 2003 Oct 8;23(27):9016–9023. doi: 10.1523/JNEUROSCI.23-27-09016.2003

Figure 3.

Figure 3.

Influence of zolantidine and thioperamide (THIOPERAM) on histamine receptor-elicited increase of p-ERK immunoreactivity in hippocampal slices. Neurons staining positive for p-ERK in hippocampi of shams (n = 9), 5 μm zolantidine (n = 3), 100 nm thioperamide (n = 13), 0.1 μm histamine (n = 4), 0.1 μm histamine plus 5 μm zolantidine (n = 5), 0.1 μm histamine plus 100 nm thioperamide (n = 6), 0.1 μm histamine plus 5 μm zolantidine plus 100 nm thioperamide (n = 6), 0.1 μm amthamine (n = 10), 0.1 μm amthamine plus 5 μm zolantidine (n = 6), 0.01 μm immepip (n = 3), and 0.01 μm immepip plus 100 nm thioperamide (n = 9). Shown are means ± SEM. **p < 0.01 and ***p < 0.001 versus sham; ###p < 0.001 versus 0.1 μm histamine; +p < 0.05 versus 0.1 μm amthamine; $$$p < 0.001 versus 0.01 immepip (ANOVA and Newman-Keuls multiple comparison test).