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. 2003 Oct 8;23(27):9016–9023. doi: 10.1523/JNEUROSCI.23-27-09016.2003

Figure 6.

Figure 6.

Effects on contextual fear conditioning of posttraining bilateral injection of amthamine, RAMH, and U0126 into the hippocampus. Immediately after training, rats were injected with 1 μl/side under general anesthesia. One microliter of a 10 μm solution of RAMH corresponded to a total amount of 1.25 ng, and 1 μl of a 1 μm solution of amthamine corresponded to 0.16 ng. Seventy-two hours after training, freezing was measured during the 6 min test period in unoperated controls (n = 10), saline-injected controls (n = 9), rats injected with 2 μg of U0126 (n = 12), 0.16 ng of amthamine (n = 12), 0.16 ng of amthamine plus 2 μg of U0126 (n = 12), 1.25 ng of RAMH (n = 10), and 1.25 ng of RAMH plus 2 μg of U0126 (n = 12). Shown are means ± SEM. *p < 0.05 versus unoperated and saline-injected control; #p < 0.05 versus amthamine; $$p < 0.01 versus RAMH (ANOVA and Newman-Keuls multiple comparison test).