Table 3.
The effect of Zn2+ on eIPSCs evoked by minimal stimulation in dentate gyrus granule cells of wt and δ−/− mice
|
|
wt |
wt + Zn2+ |
δ−/− |
δ−/− + Zn2+ |
||||
|---|---|---|---|---|---|---|---|---|
|
|
Soma
|
Dendrite
|
Soma
|
Dendrite
|
Dendrite
|
Dendrite
|
||
| Amplitude (pA) @Vh = −70mV | −119.8 ± 26.4 | −157.3 ± 16.0 | −106.2 ± 23.5 | −85.8 ± 9.3* | −104.1 ± 17.9 | −111.5 ± 13.0 | ||
| RT10-90% (msec) | 1.35 ± 0.40 | 2.98 ± 0.79 | 1.06 ± 0.21 | 3.40 ± 0.66 | 2.62 ± 0.65 | 2.90 ± 0.70 | ||
| τw (msec) | 8.2 ± 1.0 | 32.5 ± 1.1 | 7.0 ± 0.6 | 22.0 ± 1.1* | 17.8 ± 3.8 | 17.8 ± 4.1 | ||
| Number of cells
|
5
|
5
|
5
|
5
|
5
|
5
|
||
*
denotes p < 0.05, paired two tailed t test, between corresponding stimulation sites under control conditions and in the presence of 10 μm ZnCl2.