Figure 8.

Comparison of the density of perineuronal rings after different nerve lesions. Histograms show the ratios of the density of rings in DRG sections after sciatic, spinal, sural, and skin nerve lesions. Rings containing TH (black), CGRP (white), galanin (GAL, left bold hatching), and synaptophysin (Syn, right hatching). Except for the number of CGRP rings that includes coils (∼50% of total in each case), the ratios are similar. The effect of spinal nerve transection was similar to that of sciatic nerve transection. The effects of cutting four skin nerves was almost the same as that of cutting only the sural nerve except for the number of GAL+ rings. Syn+ rings were more numerous because Syn is present in varicosities of all types.