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. 2003 Nov 19;23(33):10568–10576. doi: 10.1523/JNEUROSCI.23-33-10568.2003

Figure 5.

Figure 5.

NKX6.2 expression in wild-type and Tlx mutant embryos. A, At E12.5, NKX6.2 is expressed in the sulcus between the LGE and MGE. A few scattered cells can also be detected in the LGE and MGE VZ right next to the domain of high NKX6.2 expression. B, In the Tlx mutant, NKX6.2 is ectopically expressed in the ventral half of the LGE. C, Also at E14.5, NKX6.2 expression is detected in the VZ between the LGE and MGE. D, In E14.5 Tlx mutants, the NKX6.2 expression domain in the mutants appears rather small; however, considering that the LGE is smaller in the mutant at this stage, the domain is relatively larger. In addition, NKX6.2 is ectopically expressed in scattered cells throughout much of the LGE VZ (compare insets in C and D). KO, Knock-out; Stm, striatum.