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. 2003 Dec 17;23(37):11711–11724. doi: 10.1523/JNEUROSCI.23-37-11711.2003

Figure 11.

Figure 11.

Agonist-like action of the benzodiazepine receptor antagonist flumazenil in hippocampal neurons subjected to ethanol withdrawal. A, Representative tracings of Cl- currents induced by 1 μm GABA in a control cell, a cell exposed to 100 mm ethanol for 5 d, and a cell subjected to ethanol withdrawal for 6 hr. GABA was administered in the absence or presence of flumazenil (3 μm). B, Quantitation of the modulatory effect of flumazenil on GABA-evoked Cl- currents in the three experimental groups. Data are expressed as percentage potentiation of the GABA response and are means ± SE of values from 8-25 neurons. *p < 0.01 versus value for control cells.