Table 1.
Histological properties of DRG neurons
|
|
Bladder (n = 460 cells) |
Proximal urethra (n = 364 cells) |
Distal urethra (n = 320 cells) |
|---|---|---|---|
| NF-negative C-fiber neurons | 321 cells (70%) (24.1 ± 1.5 μm) | 247 cells (68%) (24.5 ± 1.4 μm) | 163 cells (51%a) (23.5 ± 1.5 μm) |
| IB4 (+) | 58/321 (18%) | 55/247 (22%) | 80/163 (49%a) |
| IB4 (−) | 263/321 (82%) | 192/247 (78%) | 83/163 (51%a) |
| NF-positive A-fiber neurons | 139 cells (30%) (32.1 ± 1.8 μm) | 117 cells (32%) (33.3 ± 1.8 μm) | 157 cells (49%a) (36.8 ± 2.0 μm)b |
| IB4 (+) | 4/137 (3%) | 6/117 (5%) | 5/157 (3%) |
| IB4 (−)
|
133/137 (97%)
|
111/117 (95%)
|
152/157 (97%)
|
Data were obtained from four animals (six to seven DRG sections per each animal). NF, Neurofilament.
a
p < 0.05 compared with the percentage of bladder or proximal urethral neurons (ϰ2 test).
b
p < 0.05 compared with the diameter of bladder or proximal urethral neurons (t test).