Table 1.
Effect of 72 hr of 2% hypertonic saline ingestion (Hyper-) and induced hypo-osmolality (Hypo-) on mean ± SEM body weight, plasma osmolality, hematocrit, and plasma hormone concentrations
|
Hyper- (n = 6) |
Iso- (n = 6) |
Hypo- (n = 6) |
---|---|---|---|
Body weight (g) | |||
Day 1 | 290.1 ± 7.1 | 282.6 ± 4.2 | 278.6 ± 4.9 |
Day 4 | 313.4 ± 8.4 | 297.5 ± 9.1 | 286.8 ± 5.5 |
Day 4 + 72 hr | 296.5 ± 10.4 | 317.2 ± 13.6 | 295.2 ± 7.3 |
Plasma osmolality (mOsm/kg H2O) | 312.8 ± 6.4 * | 295.5 ± 0.8 * | 219.0 ± 4.7 * |
Hematocrit (%) | 45.1 ± 1.1 ** | 41.2 ± 0.5 ** | 42.9 ± 0.9 |
Plasma VP (pg/ml) | 4.2 ± 1.2 | U.D. | N/A |
Plasma OT (pg/ml) | 25.5 ± 2.3 *** | 15.7 ± 0.7 | 17.1 ± 1.9 |
Plasma T (ng/ml) | 0.5 ± 0.1 | 3.3 ± 0.6 *** | 0.3 ± 0.1 |
Plasma E2 (pg/ml)
|
5.0 ± 0.4
|
3.5 ± 0.6
|
2.9 ± 0.7
|
N/A, Data not available because of dDAVP cross-reactivity in the VP RIA; U.D., undetectable (detection limit, 1.0 pg/ml).
p <0.05 from each other
p <0.05 versus each other
p <0.05 versus the other two groups.