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. 2003 May 15;23(10):4261–4269. doi: 10.1523/JNEUROSCI.23-10-04261.2003

Table 1.

Effect of 72 hr of 2% hypertonic saline ingestion (Hyper-) and induced hypo-osmolality (Hypo-) on mean ± SEM body weight, plasma osmolality, hematocrit, and plasma hormone concentrations




Hyper- (n = 6)

Iso- (n = 6)

Hypo- (n = 6)
Body weight (g)
Day 1 290.1 ± 7.1 282.6 ± 4.2 278.6 ± 4.9
Day 4 313.4 ± 8.4 297.5 ± 9.1 286.8 ± 5.5
Day 4 + 72 hr 296.5 ± 10.4 317.2 ± 13.6 295.2 ± 7.3
Plasma osmolality (mOsm/kg H2O) 312.8 ± 6.4 * 295.5 ± 0.8 * 219.0 ± 4.7 *
Hematocrit (%) 45.1 ± 1.1 ** 41.2 ± 0.5 ** 42.9 ± 0.9
Plasma VP (pg/ml) 4.2 ± 1.2 U.D. N/A
Plasma OT (pg/ml) 25.5 ± 2.3 *** 15.7 ± 0.7 17.1 ± 1.9
Plasma T (ng/ml) 0.5 ± 0.1 3.3 ± 0.6 *** 0.3 ± 0.1
Plasma E2 (pg/ml)
5.0 ± 0.4
3.5 ± 0.6
2.9 ± 0.7

N/A, Data not available because of dDAVP cross-reactivity in the VP RIA; U.D., undetectable (detection limit, 1.0 pg/ml).

*

p <0.05 from each other

**

p <0.05 versus each other

***

p <0.05 versus the other two groups.