Figure 7.

β1-adrenoceptors are expressed, at protein level, on striatal cholinergic interneurons. A–C, CLSM image of dual-label immunofluorescence for ChAT and β1-adrenoceptors in the striatum at low magnification. A, β-1-adrenoreceptor immunoreactivity revealed by FITC (green) fluorescence; medium-sized neurons and a large neuron are immunopositive. B, ChAT immunoreactivity revealed by TRITC (red) fluorescence. C, Merged image. D–F, Same as A–C at high magnification. β1-adrenoceptors colocalize with ChAT in the cholinergic interneuron.