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. 2003 Jul 2;23(13):5437–5445. doi: 10.1523/JNEUROSCI.23-13-05437.2003

Figure 2.

Figure 2.

Line graphs showing the effects of the inhibitors of the cAMP pathway on the median mechanical withdrawal threshold 1 week after the second intramuscular acid injection. A, B, Intrathecal administration of SQ22536 (0.7 μmol) has no effect on mechanical withdrawal threshold compared with the 16% DMSO control. C, D, Intrathecal administration of PKI (60 nmol) has no effect on mechanical withdrawal threshold compared with the intrathecal saline control. INJ1, Before first intramuscular injection of pH 4.0 saline; INJ2, before second intramuscular injection of pH 4.0 saline; 1wk INJ2, 1 week after second intramuscular injection of pH 4.0 saline. Data are presented as the median with the 25th and 75th percentiles.