Scheme 1.
Formulation of functional and biocompatible FNC: (1) Synthesis of PAA polymer-coated cerium oxide nanoparticles (PNC) and (2) DiI dye encapsulating PNC. (3) Propargylated nanoceria was synthesized using carbodiimide chemistry. (4 and 5) “Click” chemistry was used to synthesize FNC, where combination of drugs was encapsulated using solvent diffusion method.