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. Author manuscript; available in PMC: 2019 Sep 12.
Published in final edited form as: Clin Cancer Res. 2017 Dec 4;24(7):1525–1535. doi: 10.1158/1078-0432.CCR-17-2451

Figure 1. rhIL-15 pharmacokinetics and cytokine responses.

Figure 1.

Blood samples were collected from enrolled subjects before, and 10 minutes, 1, 4 and 24 hours after the first dose of rhIL-15 given subcutaneously during cycle 1. Serum was frozen until batch ELISA testing was performed for IL-15 (A), IL-6 (B), and IFN-γ (C) levels, as described in Materials and Methods. Mean results from each dose cohort are shown with error bars (±1SD); the y-axis is shown in log (A) or linear scales (B, C). Error bars for panels (B) and (C) were omitted to facilitate viewing of the data because error bars for all dose cohorts overlapped, even at the 4-hour peak time point.