. 2014 Mar 6;6(4):499–514. doi: 10.1159/000358237

Table 1.

Summary of the sequences

	Total	Functional	Sequence functionality (functional/total)	Unique	Sequence diversity (unique/functional)	Clonotypes	Clonotypic diversity (clonotypes/functional)
PD15
IgM 19⁺45R^lo	36	32	0.89	32	1.0	30	0.94
IgM 19⁺45R⁺	48	45	0.94	42	0.93	42	1.0
Switched 19⁺45R^lo	118	91	0.77^a	67	0.73	23	0.34^a
Switched 19⁺45R⁺	16	9	0.56^a	8	0.88	6	0.75
PD60
IgM 19⁺45R^lo	72	68	0.94	64	0.94	58	0.96
IgM 19⁺45R⁺	66	62	0.94	61	0.98	61	1.0
Switched 19⁺45R^lo	81	55	0.68^a	51	0.92	42	0.82
Switched 19^lo45R^lo	45	22	0.49^a	22	1	21	0.95

Sequence functionality represents the number of functional sequences divided by the total number of sequences. Sequence diversity is defined as the number of unique sequences divided by the number of functional sequences. Each clonotype includes sequences that use the same VH gene, and that have a highly homologous CDR-H3 and an identical CDR-H3 length. Clonotypic diversity is defined as the number of clonotypes divided by the number of functional sequences.

p < 0.05: data were compared in contingency tables with the χ² test.