Fig. 3.

Neutrophil influx into the lungs of WT and sigirr−/− mice during pneumococcal pneumonia. Neutrophil numbers in WT and sigirr−/− lung tissue were evaluated via Ly-6 staining of lung slides (a-e) during pneumonia. Neutrophil numbers were further counted in BAL fluid 6 h after inoculation (f). Representative Ly-6-stained lung sections of WT (b, d) and sigirr−/− mice (c, e) are depicted 6 (b, c) and 48 h (d, e) after the induction of pneumonia; original magnification ×10. Data in a and f are the means ± SEM of 8 mice per group at each time point.