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Edema formation in the lung. Mice were treated with the Rho-kinase inhibitor Y-27632 (0.5 or 5 mg/kg) or vehicle (PBS) 10 min prior to M1 protein injection. Mice treated with PBS served as sham animals. One group of mice was given 5 mg/kg Y-27632 alone without M1 protein injection. Data represents mean ± SEM, * p < 0.05 versus sham and # p < 0.05 versus vehicle + M1 protein, n = 5.
