Table 2.
Cells responsive to IFN-λ
| Cells/organs | Reference No. | ||
|---|---|---|---|
|
Responsive cells (mouse) Cell lines | |||
| B16 melanoma cells | 5 | ||
| PAM212 keratinocyte-like cells | 5 | ||
| Primary cells | |||
| Keratinocytes | 5 | ||
| Vaginal epithelial cells | 12 | ||
| pDCs | 12 | ||
| In vivo | |||
| Kidney (epithelial cells) | 19, 20 | ||
| Epithelial cells of the choroid plexus | 19 | ||
| Intestine (epithelial cells) | 17, 20 | ||
| Airway cells | 13 – 15, 20 | ||
| Salivary glands | 20 | ||
| Cholangiocytes | 30 | ||
|
Responsive cells (human) Cell lines | |||
| HepG2, HuH7 (hepatocytes) | 8, 18, 52, 62 | ||
| HeLa | 1 | ||
| HaCaT (keratinocytes) | 1 | ||
| A594 (lung carcinoma cells) | 1 | ||
| Intestinal cell lines | 1, 63 | ||
| Primary cells | |||
| Hepatocytes | 18 | ||
| Keratinocytes | 21, 62, 64 | ||
| Melanocytes | 62 | ||
| Natural killer cells | 62 | ||
| Airway epithelial cells | 65 | ||
| Nasal epithelial cells | 66 | ||
| Astrocytes | 67 | ||
| Neurons | 67 | ||
| pDCs | 24 | ||
| DCs | 25 | ||
| Monocytes | 62 | ||
| In vivo | |||
| Liver | 53, 54 | ||
|
Nonresponsive cells (human and mouse) Cell lines | |||
| Fibroblasts | 5 | ||
| Primary cells | |||
| Lymphocytes | 12, 26 | ||
| Monocytes, macrophages | 5, 12, 62 | ||
| Endothelial cells | 62 | ||
| Fibroblasts | 12 | ||
| Adipocytes | 62 | ||
| Splenocytes | 5 | ||
| In vivo | |||
| Adipocytes | 19 | ||
| Endothelial cells | 19 | ||
| Hepatocytes (mouse) | 30 | ||