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. 2019 May 23;76(15):2917–2932. doi: 10.1007/s00018-019-03145-x

Table 1.

List of PRMTs whose structures have been reported in the PDB

PRMTs List of PDB I.D.
PRMT1 1ORI (AdoHcy), 1ORH (AdoHcy, P), 1OR8 (AdoHcy, P), 3Q7E (AdoHcy)
PRMT2 5G02 (S), 5FUB (AdoHcy), 5JMQ
PRMT3 4HSG (I), 1F3L (AdoHcy), 4QQN (C), 4RYL (I), 2FYT (AdoHcy), 3SMQ (I), 1WIR
PRMT4/CARM1 5U4X (I), 4IKP (S), 5IH3 (AdoHcy), 5IS6 (S), 5IS7 (AdoHcy), 5IS8 (I), 5IS9 (I), 5ISB (I), 5ISC (I), 5ISD (I), 5ISE (I), 5ISF (I), 5ISG (I), 5ISH (I), 5ISI (I), 5K8 V (C), 5K8 W (I), 5K8X (I), 5LGS (L), 5TBH (I), 5TBI (I), 5TBJ (I), 3B3F (AdoHcy), 3B3G, 3B3 J
PRMT5a 4G56 (AdoMet), 4GQB (OXU, P), 4X60 (I, S), 4X61 (AdoMet, I), 4X63 (AdoHcy, I), 5EMJ (C, S), 5EMK (C, S), 5EML (C, AdoMet), 5EMM(C, S), 5FA5 (C, P), 5C9Z (I, S), 6CKC (I), 3UA3 (AdoHcy), 3UA4
PRMT6 4C03, 4C04 (I), 4C05 (AdoHcy), 4C06, 4C07, 4C08, 4Y2H(AdoHcy, I), 4Y30(AdoHcy, I), 5EGS(I), 5FQN (AdoHcy), 5FQO (AdoHcy) 5LV4 (I), 5LV5 (I), 4LWO, 4LWP (AdoHcy), 4QQK, (I), 4HC4 (AdoHcy), 5HZM (AdoHcy), 4QPP (AdoHcy, I), 5E8R (AdoHcy, I), 5WCF (AdoHcy, I)
PRMT7 3WST (AdoHcy), 3X0D (AdoHcy), 5EKU (AdoHcy), 4C4A (AdoHcy), 4M36, 4M37 (AdoHcy), 4M38 (AdoHcy, P), 6NPG (I)
PRMT8 4X41(AdoHcy), 5DST(AdoHcy)
PRMT9 N/A

I inhibitor, S sinefungin, C compound, P peptide

avertebrate PRMT5 form a complex with MEP50