Table 3.
PRMT type and PDB ID | Peptide sequence detail | Peptide type |
---|---|---|
RnPRMT1 (1ORH) | GGFGGRGGFG | R3 (AdoHcy) |
RnPRMT1 (1OR8) | Chain-b 1-GGRGGFGGRGGFGGRGGFG-19 | R3 (AdoHcy) |
Chain-c 1-GGRGGFGGRGGFGGRGGFG-19 | ||
Chain-d 1-GGRGGFGGRGGFGGRGGFG-19 | ||
Chain-e 1-E1GGRGGFGGRGGFGGRGGFG-19 | ||
HsPRMT5 (4GQB) | 1-SGRGKGGKGLGKGGAKRHRKV-21 | Histone H4 (OXU) |
HsPRMT5 (5FA5) | 1-SGRGKGGKGLGKGGAKRHRK-21 | Histone H4 (MTA) |
TbPRMT7 (4M38) | 1-SGRGKGGKGLGKGGAKRHRKV-21 | Histone H4 (AdoHcy) |
For the R3 peptide (PDB ID: 1OR8) the arginine position is shown
Residues that has only revealed peptide backbone are shown as bold characters; residues containing no electron density in the crystal structure are shown as regular characters. Residues with clear electron density of the side chain and backbone are shown as bold and italic characters. Co-substrates are shown in parentheses