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. 2019 Sep 3;55(4):845–859. doi: 10.3892/ijo.2019.4867

Figure 1.

Figure 1

Hypoxia downregulates CX26 and CX43 in PECs. (A) Positive expression of CX26 and CX43 was decreased in cancer tissues as detected by immunohistochemistry (×400; scale bar, 25 µm; n=60). (B) mRNA expression of CX26 and CX43 in pulmonary epithelial tissue as determined by RT-qPCR (n=60). (C) Protein expression of CX26 and CX43 in pulmonary epithelial tissue, as assessed by western blot analysis (n=60). *P<0.05 vs. paracancerous tissues. (D) mRNA expression of CX26 and CX43 in PECs, as determined by RT-qPCR (n=3). (E) Protein expression of CX26 and CX43 in PECs, as assessed by western blot analysis (n=3). #P<0.05 vs. normal group. PECs, pulmonary epithelial cells; RT-qPCR, reverse transcription-quantitative PCR; CX, connexin.