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. 2019 Aug 5;55(4):789–804. doi: 10.3892/ijo.2019.4854

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Copyright: © Yusufu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Two-way hierarchical cluster analysis of 21 cancer tissue and 10 normal tissue samples (columns) and DNA-methylation of CpG Units in promoter regions (rows). DNA-methylation levels are depicted in this heatmap on a continuous scale from light green (unmethylated) to light red (100% methylated). Poor quality data is shown in black. Less-dominant clustering was found in cancer or normal tissues. The hierarchical cluster algorithm could not separate colon cancer samples from normal tissue samples.