Table 2. Combinations of coding changes detected in the QRDR and their frequency by country of reported travel.

Country	Region	Gene combination (with amino acid change)	Frequency
China	Central Asia	gyrA-S83F	1
Rwanda	East Africa	gyrA-S83Y	1
Tanzania		gyrA-D87G	2
Uganda		gyrA-S83Y	4
Zimbabwe		gyrA-D87Y	2
Greece	Europe	gyrA-S83F	1
Iraq	Middle East	gyrA-S83F	1
United Arab Emirates		gyrA-S83F	1
Egypt	North Africa	gyrA-D87G	1
Peru	South America	gyrA-S83F	1
Afghanistan	South Asia	gyrA-S83F	1
Bangladesh		gyrA-S83F	25
		gyrA-S83F parC-E84K	2
		gyrA-S83Y	1
		gyrA-D87N	3
India		gyrA-S83F gyrA-D87G parC-S80I	1
		gyrA-S83F gyrA-D87N parC-S80I	41
		gyrA-S83F	71
		gyrA-S83F parC-G78D	2
		gyrA-S83F parC-S80I	4
		gyrA-S83F parC-E84G	2
		gyrA-S83Y	56
		gyrA-S83Y parC-Y74X parC-P98X	1
		gyrA-S83Y parC-D79G	5
		gyrA-D87N	2
		gyrA-D87Y	1
Nepal		gyrA-S83F gyrA-D87N parC-S80I	1
		gyrA-D87G	1
Pakistan		gyrA-S83F gyrA-D87N parC-S80I	6
		gyrA-S83F	134
		gyrA-S83F *	1
		gyrA-S83Y	1
		gyrA-D87G	2
		gyrA-D87N	2
Malaysia	South East Asia	gyrA-S83F	1
Myanmar		gyrA-S83F	1
		gyrA-D87N	1
Nigeria	West Africa	gyrA-S83Y	3
No Travel Information	No information	gyrA-S83F gyrA-D87N parC-S80I	4
		gyrA-S83F	16
		gyrA-S83F parC-E84K	1
		gyrA-S83Y	9
		gyrA-D87G	2
		gyrA-D87N	3
		gyrA-D87Y	1
No Travel	None	gyrA-S83F gyrA-D87N parC-S80I	2
		gyrA-S83F	15
		gyrA-S83Y	3

* The acquired quinolone resistance (qnr) gene, qnrB, was also detected in this isolate. The only other qnr genes detected were two isolates from Zimbabwe that carried qnrS1 genes but no QRDR mutations.

The three most common point mutations are bolded. Isolates from cases with reported travel to multiple countries not included in table.