Fig. 1.
Expression of BETA2/NeuroD1 in the developing and adult retina. A–F, X-gal staining from +/− mice at E10.5, E13, E16.5, E18.5, P3, and P30. G–L, X-gal staining from −/− mice at the same time points. The pattern of expression is similar for +/− and −/− mice all time points. However, null mice display a higher level of expression because of the presence of two copies of the β-gal gene. At earlier time points (A, B and G, H) BETA2/NeuroD1 is expressed central to the peripheral pattern in both the inner and outer retina. High levels of expression are seen in the outer layers of the retina, and punctate staining is seen in the ganglion cell layer.