Table 2.
Brain regions in which anesthesia-induced neurodegeneration was most heavily concentrated
| Brain region | Severity (fold increase) |
|---|---|
| Medial septal nucleus | 27 |
| Diagonal band of Broca | 29 |
| Nucleus accumbens | 33 |
| Rostral caudate nucleus | 26 |
| Globus pallidus | 43 |
| Amygdaloid nuclei | |
| Basolateral | 22 |
| Medial | 25 |
| Cortical | 23 |
| Thalamic nuclei | |
| Paraventricular | 34 |
| Anterodorsal | 28 |
| Anteroventral | 57 |
| Anteromedial | 51 |
| Laterodorsal | 68 |
| Reuniens | 34 |
| Parafascicularis | 45 |
| Hippocampus, rostral CA1 | 21 |
| Subiculum | 58 |
| Cingulate cortex | 32 |
| Retrosplenial cortex | 53 |
| Neocortex (layers II and IV) | |
| Frontal | 18 |
| Parietal | 34 |
| Temporal | 22 |
| Occipital | 35 |
| Hypothalamus | |
| Anterior | 22 |
| Ventromedial | 34 |
| Dorsomedial | 21 |
| Mammillary complex | 33 |
Severity is expressed as the fold increase (i.e., how many times greater the density of degenerating neurons was in the experimental brain compared with the baseline rate of degeneration in the same region of control brain).