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. 2003 Feb 1;23(3):748–757. doi: 10.1523/JNEUROSCI.23-03-00748.2003

Fig. 7.

Fig. 7.

Rin1 mutants have normal motor learning and open field performance. A, Accelerating rotarod. Wild-type (n = 12) andRin1−/− (n = 11) mice were given five trials in an accelerating rotarod (4–40 rpm in 5 min) during a single day. All subjects showed an increased latency to fall across trials (F(4,84) = 17.4;p < 0.05). In addition, both groups of animals fell off the rotating rod at the same time, indicating equivalent learning rates across trials (F(4,84) = 0.4; p > 0.05), with no effect of genotype (F(1,21) = 0.3; p> 0.05). B, Open field path length. Mice were placed in the center of a white circular arena (60 cm in diameter) and tracked for 5 min. Mean path length for mutant (n = 12; 2992 ± 352 cm) and wild type (n = 14; 2501 ± 215 cm) were equivalent (F(1,24) = 1.5; p> 0.05). C, Open field inner and outer zone exploratory behavior. Mutant and wild-type mice were equivalent in percentage of time exploring the inner and outer zones (F(1,24) = 0.5; p> 0.05).