Responding under a second-order schedule of reinforcement in WT(+/+) and gria1 KO(−/−) mice.A, Mean number of reinforcers (rfcs) obtained during a 60 min session under each schedule. Sessions were conducted on consecutive days. B, Mean time required to obtain the first reinforcer (rfc) under each schedule. Sessions were conducted on consecutive days. *p < 0.05 for all schedules compared with WT mice. C, Top, Percentage of mice reaching the criterion at each schedule, over the course of eight sessions, during the acquisition phase of the second-order schedule. Bottom, Percentage of mice from each genotype that reached the criterion within five sessions. Error bars indicate SEM. The vertical dotted lines separate the phases of the second-order training.