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. 2003 Mar 1;23(5):1678–1687. doi: 10.1523/JNEUROSCI.23-05-01678.2003

Fig. 7.

Fig. 7.

Effects of glutamate on the openings of the 71 and 161 pS single-channel KCa currents in cell-attached patches of cultured astrocytes recorded at a patch potential (pp) of 60 mV using symmetrical KCl (145 mm) solution. A, Representative tracings of single-channel KCa currents under control conditions and after addition of 100 or 300 μm glutamate to the bath.C represents the closed state of the channel.B, Summary of effects of glutamate (30–300 μm) on the NPo of the 71 pS (open bars) and the 161 pS (filled bars) single-channel KCa currents. Glutamate beginning at 100 μm significantly increased the opening frequencies and NPo of both the 71 and 161 pS KCa channel currents. Vertical linesrepresent mean ± SEM. The asterisk denotes significant difference from the respective controls (p < 0.05; n = 7–12 cells).