Table 1.
Sham | Trained | |||||
---|---|---|---|---|---|---|
No drug | Clonidine | Effect | No drug | Clonidine | Effect | |
Effect of clonidine | ||||||
Monosynaptic excitation | 2.55 | 2.69 | 1.65 | 1.66 | ||
Disynaptic inhibition | −3.01 | −2.09 | ↓30.5% | −2.75 | −1.07 | ↓61.0% |
Polysynaptic excitation | 0.09 | 0.60 | ↑535.6% | 0.17 | 0.68 | ↑307.8% |
Occurrence of reversals | 8 of 94 | 12 of 40 | ↑21.5% | 9 of 103 | 30 of 77 | ↑30.2% |
Without drug | With clonidine | |||||
---|---|---|---|---|---|---|
Sham | Trained | Effect | Sham | Trained | Effect | |
Effect of training | ||||||
Monosynaptic excitation | 2.55 | 1.65 | 2.69 | 1.66 | ||
Disynaptic inhibition | −3.01 | −2.75 | −2.09 | −1.07 | ↓48.7% | |
Polysynaptic excitation | 0.09 | 0.17 | 0.60 | 0.68 | ||
Occurrence of reversals | 8 of 94 | 9 of 103 | 12 of 40 | 30 of 77 |
Only statistically significant changes are indicated.