Table 2.

Maternal viral infection affects social behavior in adult offspring

	Number of times in contact	Time to first contact
Mice born to sham infected mothers	8.4  ± 1.7	24.6  ± 6.8
Mice born to infected mothers	3.1  ± 0.9	111.4  ± 39.1
	p < 0.01	p < 0.07

The same mice used in the exploratory behavior tests were assayed (as pairs from the same groups) 1–2 d later in a social interaction test. The times, in seconds, of each behavior during the 5 min test period were graded from videotapes, and the significance of the differences assessed by a two-tailed t test. Data are given as mean ± SEM. Seven pairs of controls (4 female and 3 male pairs) and 10 pairs of mice born to infected mothers (5 female and 5 male pairs) were used.